The Human Toxome Project is a collaboration of Environmental Working Group and Commonweal. These organisations are committed to researching and presenting a number of enviromental impact studies.
| Health concern or target organ | Chemical families |
| Birth defects and developmental delays | Bisphenol A, Chlorinated dioxins & furans, Volatile and semivolatile organic compounds (VOCs and SVOCs), Lead, Mercury, Methylmercury, Organochlorine Pesticides (OCs), Perchlorate, Perfluorochemicals (PFCs), Phthalates, Polychlorinated biphenyls (PCBs), Metals |
| Brain and nervous system | Lead, Mercury, Methylmercury, Organophosphate Pesticide metabolites (OPs), Polybrominated diphenyl ethers (PBDEs), Polychlorinated biphenyls (PCBs), Metals |
| Cancer | Arsenic (inorganic only), Bisphenol A, Cadmium, Chlorinated dioxins & furans, Chromium, Volatile and semivolatile organic compounds (VOCs and SVOCs), Organochlorine Pesticides (OCs), Perfluorochemicals (PFCs), Polyaromatic hydrocarbons (PAHs), Polychlorinated biphenyls (PCBs), Nitro- and polycylic- musks, Metals, Parabens |
| Endocrine system | Alkylphenols, BADGE-4OH, Bisphenol A, Bisphenol A & BADGE, Perchlorate, Perfluorochemicals (PFCs), Phthalates, Triclosan, Nitro- and polycylic- musks, Parabens |
| Gastrointestinal (including liver) | Arsenic (inorganic only), Polychlorinated naphthalenes (PCNs) |
| Hematologic (blood) system | Perchlorate |
| Immune system (including sensitization and allergies) | Bisphenol A & BADGE, Brominated dioxins & furans, Chlorinated dioxins & furans, Polychlorinated biphenyls (PCBs) |
| Kidney and renal system | Cadmium, Volatile and semivolatile organic compounds (VOCs and SVOCs) |
| Reproduction and fertility | Alkylphenols, Bisphenol A, Organochlorine Pesticides (OCs), Phthalates, Polyaromatic hydrocarbons (PAHs), Polybrominated diphenyl ethers (PBDEs) |
| Skin | BADGE-4OH, Polychlorinated naphthalenes (PCNs), Triclosan, Parabens |
References
References – open scientific literature
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[5] ATSDR, CERHR
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References – Government, academic, and industry databases
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References – Health effect summaries for toxome chemicals
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[9] 3M (2000). “3M to pare Scotchgard products: one long-lasting compound is cited (Comment by Charles Reich, Executive Vice President of Specialty Material Markets for 3M).” The Washington Post. May 17, 2000. “It was a complete surprise that it [PFOS] was in the blood bank supplies.” – Charles Reich, Executive Vice President of Specialty Material Markets for 3M, The Washington Post, May 17, 2000
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[13] 3M (2001). Final Report, A Longitudinal Analysis of Serum Perfluorooctanesulfonate (PFOS) and Perfluorooctanoate (PFOA) in Relation to Clinical Chemistry, Thyroid Hormone, Hematology and Urinalysis Results from Male and Female Employee Participants of the 2000.
[14] 3M (2002). Analysis of pooled human sera and plasma and monkey sera for fluorocarbons using exygen method ExM-023-071. Report prepared for 3M, St. Paul, MN by Exygen Research, State College, PA. Sponsor study number E02-1071; Exygen Study Number: 023-082 U.S. .
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